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Developmental dysplasia of the hip or hip osteoarthritis

near SUPT3H · rs1384547

Where this position leads

Condition: Hip Osteoarthritis

rs1384547 Condition: Hip Osteoarthritis Hip Osteoarthritis Condition rs1384547 rs1384547 near SUPT3H

What the study found

Who was studied 36,445 European ancestry cases, 316,943 European ancestry controls, 1,085 Japanese ancestry cases, 24,000 Japanese ancestry controls.

The effect Each copy of the T allele carried 0.94 times the odds of Developmental dysplasia of the hip or hip osteoarthritis (95% confidence interval 0.919-0.954); p = 2 × 10−12.

How common The T allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — between genes, 177.4 kb from SUPT3H.

What each result means

C/C No copy of the version the research linked to Developmental dysplasia of the hip or hip osteoarthritis. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Developmental dysplasia of the hip or hip osteoarthritis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Developmental dysplasia of the hip or hip osteoarthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source
Genetic study identifies novel genes in developmental dysplasia of the hip
Yoshino S, Chen S, Yamaguchi R, Kurakazu T, Hatzikotoulas K, Koike Y, Inoue D, Kohno Y, Sasaki K, Choe H, Baba S, Hara T
and 31 more — show all
Ito J, Okuzu Y, Shiomoto K, Nakamura T, Koyano G, Shimizu T, Kinoshita K, Takahashi E, Utsunomiya T, Hara D, Sato T, Kawahara S, Kaneuji A, Yamamoto T, Takahashi D, Jinno T, Kawano T, Goto K, Takagi M, Mawatari T, Inaba Y, Nakamura T, Kabata T, Hamai S, Motomura G, Southam L, Wilkinson JM, Zeggini E, Ikegawa S, Nakashima Y, Terao C
Bone research · 2026 · PMID 41912496 · open access

Questions about rs1384547

What is rs1384547?

rs1384547 is a single position in the genome, in or near the near SUPT3H gene. Published research associates it with developmental dysplasia of the hip or hip osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1384547 linked to?

On MyGeneLog this position is linked to Hip Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs1384547 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1384547 come from?

GWAS Catalog, Bone research 2026, PMID:41912496. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Developmental dysplasia of the hip or hip osteoarthritis (rs1384547). MyGeneLog™. https://www.mygenelog.com/variants/rs1384547

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