0 1714624Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot6Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 243 African American or Afro-Caribbean cases, 120,331 African American or Afro-Caribbean controls, 642 European ancestry cases, 446,916 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 3.73 lower (95% confidence interval 3.72-3.75); p = 7 × 10−13.
How common The G allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 6, band 6q27 — a synonymous change in DLL1.
What ClinVar records
ClassificationLikely benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2025-12-10.
ClinVar record 721276NM_005618.4(DLL1):c.573C>T (p.Phe191=)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ANo copy of the version the research linked to Acute laryngitis and tracheitis (PheCode 465.4). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Acute laryngitis and tracheitis (PheCode 465.4). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Acute laryngitis and tracheitis (PheCode 465.4). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs138404838
What is rs138404838?
rs138404838 is a single position in the genome, in or near the DLL1 gene. Published research associates it with acute laryngitis and tracheitis (phecode 465.4). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs138404838 linked to?
On MyGeneLog this position is linked to Acute Laryngitis and Tracheitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs138404838 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs138404838 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1714624Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot6Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Acute laryngitis and tracheitis (PheCode 465.4) (rs138404838). MyGeneLog™. https://www.mygenelog.com/variants/rs138404838