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Survival in sepsis

LINC00378 · rs138347802

What the study found

Who was studied 506 European ancestry survivors, 181 European ancestry non-survivors; replicated in 712 European ancestry survivors, 650 European ancestry non-survivors, 411 African American survivors, 290 African American non-survivors.

The effect Each copy of the G allele carried 2.57 times the odds of Survival in sepsis (95% confidence interval 1.82-13.03); p = 4 × 10−8.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 13, band 13q21.2 — in an intron of LINC00378.

What each result means

A/A No copy of the version the research linked to Survival in sepsis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Survival in sepsis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Survival in sepsis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs138347802

What is rs138347802?

rs138347802 is a single position in the genome, in or near the LINC00378 gene. Published research associates it with survival in sepsis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs138347802 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138347802 come from?

GWAS Catalog, Critical care (London, England) 2022, PMID:36335405. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Survival in sepsis (rs138347802). MyGeneLog™. https://www.mygenelog.com/variants/rs138347802

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