Standard

Thrombin generation potential phenotypes

PTPRJ · rs138315285

Where this position leads

Condition: Fibrinogen and Blood Clotting

rs138315285 Condition: Fibrinogen and Blood Clotting Fibrinogen and Blood Clotting Condition rs138315285 rs138315285 PTPRJ

What the study found

Who was studied 714 European ancestry venous thrombosis cases, 1,253 European ancestry individuals; replicated in 714 European ancestry venous thrombosis cases, 543 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 35.8 nM higher (95% confidence interval 25.11-46.51); p = 6 × 10−11.

Where it sits Chromosome 11, band 11p11.2 — in an intron of PTPRJ.

What each result means

A/A Two copies of the version the research linked to Thrombin generation potential phenotypes. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Thrombin generation potential phenotypes. That is a smaller link than two copies.
G/G No copy of the version the research linked to Thrombin generation potential phenotypes. This is the starting point the study compared everyone against.
Source

Questions about rs138315285

What is rs138315285?

rs138315285 is a single position in the genome, in or near the PTPRJ gene. Published research associates it with thrombin generation potential phenotypes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs138315285 linked to?

On MyGeneLog this position is linked to Fibrinogen and Blood Clotting. The research behind each link, and its sources, are set out on that condition page.

Does having rs138315285 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs138315285 come from?

GWAS Catalog, Blood 2013, PMID:24357727. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Thrombin generation potential phenotypes (rs138315285). MyGeneLog™. https://www.mygenelog.com/variants/rs138315285

← See all variants