Who was studied 4,921 European ancestry cases, 450,694 European ancestry controls, 1,665 East Asian ancestry cases, 175,288 East Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 7.12 higher (95% confidence interval 4.57-9.67); p = 4 × 10−8.
Where it sits Chromosome 15, band 15q22.31 — in an intron of CIAO2A.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Cystitis — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cystitis.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cystitis compared to the general population.
rs138137126 is a single position in the genome, in or near the CIAO2A gene. Published research associates it with cystitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs138137126 linked to?
On MyGeneLog this position is linked to Colon Polyp. The research behind each link, and its sources, are set out on that condition page.
Does having rs138137126 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs138137126 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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