Sensitive

Diverticular disease

near CCN3 · rs1381333

Where this position leads

Condition: Diverticular Disease

rs1381333 Condition: Diverticular Disease Diverticular Disease Condition rs1381333 rs1381333 near CCN3

What the study found

Who was studied 56,355 European ancestry cases, 398,413 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.06 higher (95% confidence interval 0.046-0.074); p = 5 × 10−21.

How common The C allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 8, band 8q24.12 — between genes, 1.1 kb from CCN3.

What each result means

C/C Two copies of the version the research linked to Diverticular disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Diverticular disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Diverticular disease. This is the starting point the study compared everyone against.
Source

Questions about rs1381333

What is rs1381333?

rs1381333 is a single position in the genome, in or near the near CCN3 gene. Published research associates it with diverticular disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1381333 linked to?

On MyGeneLog this position is linked to Diverticular Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs1381333 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1381333 come from?

GWAS Catalog, Cell genomics 2023, PMID:37492107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diverticular disease (rs1381333). MyGeneLog™. https://www.mygenelog.com/variants/rs1381333

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