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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,382,012 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.00535 higher (95% confidence interval 0.0038-0.0069); p = 4 × 10−11.
How common The G allele had a frequency of about 65% in the people studied.
Where it sits Chromosome 22, band 22q13.2 — in an intron of EFCAB6.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Smoking initiation — no copies of the reported risk allele.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Smoking initiation.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Smoking initiation compared to the general population.
rs137793 is a single position in the genome, in or near the EFCAB6 gene. Published research associates it with smoking initiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs137793 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs137793 come from?
GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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