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Biological sex

near CRLF3P1 · rs1368546

What the study found

Who was studied 1,301,549 European ancestry cases, 1,160,583 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0112 higher (95% confidence interval 0.0076-0.0148); p = 1 × 10−9.

Where it sits Chromosome 2, band 2q12.1 — between genes, 53.3 kb from CRLF3P1.

What each result means

C/C No copy of the version the research linked to Biological sex. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Biological sex. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Biological sex. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1368546

What is rs1368546?

rs1368546 is a single position in the genome, in or near the near CRLF3P1 gene. Published research associates it with biological sex. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1368546 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1368546 come from?

GWAS Catalog, Nature genetics 2021, PMID:33888908. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Biological sex (rs1368546). MyGeneLog™. https://www.mygenelog.com/variants/rs1368546

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