Standard
Prostate-specific antigen levels
KLK2 · rs1354774
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Prostate-specific antigen levels — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Prostate-specific antigen levels.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Prostate-specific antigen levels compared to the general population.
Source
Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA
Jin G,
Zheng SL,
Lilja H,
Kim ST,
Tao S,
Gao Z,
Young T,
Wiklund F,
Feng J,
Isaacs WB,
Rittmaster RS,
Gronberg H
and 3 more — show all
Neoplasia (New York, N.Y.) · 2013 · PMID 23359319
Questions about rs1354774
What is rs1354774?
rs1354774 is a single position in the genome, in or near the KLK2 gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1354774 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1354774 come from?
GWAS Catalog, Neoplasia 2013, PMID:23359319. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants