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Thyroid stimulating hormone levels within normal range in pregnancy

LINC01586 · rs1348003

What the study found

Who was studied 67,471 Chinese ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.124 lower (95% confidence interval 0.11-0.14); p = 1 × 10−54.

How common The C allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 15, band 15q26.1 — in an intron of LINC01586.

What each result means

C/C Two copies of the version the research linked to Thyroid stimulating hormone levels within normal range in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Thyroid stimulating hormone levels within normal range in pregnancy. That is a smaller link than two copies.
G/G No copy of the version the research linked to Thyroid stimulating hormone levels within normal range in pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs1348003

What is rs1348003?

rs1348003 is a single position in the genome, in or near the LINC01586 gene. Published research associates it with thyroid stimulating hormone levels within normal range in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1348003 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1348003 come from?

GWAS Catalog, Nature communications 2024, PMID:39266554. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thyroid stimulating hormone levels within normal range in pregnancy (rs1348003). MyGeneLog™. https://www.mygenelog.com/variants/rs1348003

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