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Who was studied 67,062 European ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 4 × 10−12.
How common The T allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 12, band 12p11.1 — in an intron of SYT10.
What each result means
C/CNo copy of the version the research linked to Resting heart rate. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Resting heart rate. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Resting heart rate. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29769521 · open access
Questions about rs1343676
What is rs1343676?
rs1343676 is a single position in the genome, in or near the SYT10 gene. Published research associates it with resting heart rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1343676 linked to?
On MyGeneLog this position is linked to Resting Heart Rate. The research behind each link, and its sources, are set out on that condition page.
Does having rs1343676 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1343676 come from?
GWAS Catalog, Nature communications 2018, PMID:29769521. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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