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Serum alkaline phosphatase levels

INPP5D · rs13418066

What the study found

Who was studied 390,964 European ancestry individuals; replicated in 105,030 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 6.31 z-score higher; p = 3 × 10−10.

How common The C allele had a frequency of about 51% in the people studied.

Where it sits Chromosome 2, band 2q37.1 — inside ATG16L1.

What each result means

A/A No copy of the version the research linked to Serum alkaline phosphatase levels. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Serum alkaline phosphatase levels. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Serum alkaline phosphatase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13418066

What is rs13418066?

rs13418066 is a single position in the genome, in or near the INPP5D gene. Published research associates it with serum alkaline phosphatase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13418066 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13418066 come from?

GWAS Catalog, Nature communications 2021, PMID:33547301. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum alkaline phosphatase levels (rs13418066). MyGeneLog™. https://www.mygenelog.com/variants/rs13418066

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