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Who was studied 252,438 European ancestry cases, 1,959,739 European ancestry controls, 9,826 East Asian ancestry cases, 140,446 East Asian ancestry controls, 754 South Asian ancestry cases, 52,054 South Asian ancestry controls, 9,485 African ancestry cases, 109,006 African ancestry controls, 3,447 Admixed American ancestry cases, 46,818 Admixed American ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0221 lower (95% confidence interval 0.016-0.029); p = 4 × 10−11.
How common The T allele had a frequency of about 50% in the people studied.
Where it sits Chromosome 2, band 2q22.3 — between genes, 62.1 kb from RNU7-2P.
What each result means
G/GPublished research associates this genotype with typical/baseline likelihood of Atrial fibrillation — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Atrial fibrillation.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Atrial fibrillation compared to the general population.
Nature communications · 2025 · PMID 40645996 · open access
Questions about rs13404882
What is rs13404882?
rs13404882 is a single position in the genome, in or near the near RNU7-2P gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs13404882 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs13404882 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13404882 come from?
GWAS Catalog, Nature communications 2025, PMID:40645996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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