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Non-HDL cholesterol levels

KCNK3 · rs13394970

What the study found

Who was studied 1,320,016 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0142 lower (95% confidence interval 0.011-0.018); p = 5 × 10−13.

How common The T allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 2, band 2p23.3 — in an intron of KCNK3.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Non-HDL cholesterol levels — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Non-HDL cholesterol levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Non-HDL cholesterol levels compared to the general population.
Source

Questions about rs13394970

What is rs13394970?

rs13394970 is a single position in the genome, in or near the KCNK3 gene. Published research associates it with non-hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13394970 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13394970 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Non-HDL cholesterol levels (rs13394970). MyGeneLog™. https://www.mygenelog.com/variants/rs13394970

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