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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 67 European ancestry Alzheimer's disease cases, 323 European ancestry mild cognitive impairment cases, 196 European ancestry individuals with normal cognition.
The effect
Each copy of the T allele shifted the measure 0.027 lower; p = 2 × 10−8.
Where it sits Chromosome 2, band 2p24.1 — between genes, 43.6 kb from LINC01808.
What each result means
C/CNo copy of the version the research linked to Cerebral glucose metabolic decline (left angular gyrus). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cerebral glucose metabolic decline (left angular gyrus). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cerebral glucose metabolic decline (left angular gyrus). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs13387360 is a single position in the genome, in or near the near OSR1 gene. Published research associates it with cerebral glucose metabolic decline (left angular gyrus). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs13387360 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13387360 come from?
GWAS Catalog, Journal of Alzheimer's disease : JAD 2020, PMID:32804141. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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