Sensitive

Non-cardia gastric cancer

PRKAA1 · rs13361707

Where this position leads

Condition: Non-Cardia Gastric Cancer

rs13361707 Condition: Non-Cardia Gastric Cancer Non-Cardia Gastric Cancer Condition rs13361707 rs13361707 PRKAA1

What the study found

Who was studied 2,031 Han Chinese ancestry cases, 4,970 Han Chinese ancestry controls; replicated in 3,564 Han Chinese ancestry cases, 4,637 Han Chinese ancestry controls.

The effect Each copy of the C allele carried 1.32 times the odds of Non-cardia gastric cancer (95% confidence interval 0.88-1.43); p = 1 × 10−10.

How common The C allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 5, band 5p13.1 — in an intron of PRKAA1.

What each result means

C/C Two copies of the version the research linked to Non-cardia gastric cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Non-cardia gastric cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Non-cardia gastric cancer. This is the starting point the study compared everyone against.
Source

Questions about rs13361707

What is rs13361707?

rs13361707 is a single position in the genome, in or near the PRKAA1 gene. Published research associates it with non-cardia gastric cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13361707 linked to?

On MyGeneLog this position is linked to Non-Cardia Gastric Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs13361707 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13361707 come from?

GWAS Catalog, Gut 2015, PMID:26701879. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Non-cardia gastric cancer (rs13361707). MyGeneLog™. https://www.mygenelog.com/variants/rs13361707

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