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Verbal declarative memory

ISL1 · rs13360092

What the study found

Who was studied Up to 27,337 European ancestry individuals, up to 472 Korkulan individuals, up to 1,267 Erasmus Rucphen Family individuals; replicated in Up to 10,617 European ancestry individuals, up to 3,811 African American individuals.

The effect Each copy of the A allele shifted the measure 0.765 lower (95% confidence interval 0.5-1.04); p = 3 × 10−8.

How common The A allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 5, band 5q11.1 — between genes, 65.7 kb from RNU6-1296P.

What each result means

A/A Two copies of the version the research linked to Verbal declarative memory. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Verbal declarative memory. That is a smaller link than two copies.
G/G No copy of the version the research linked to Verbal declarative memory. This is the starting point the study compared everyone against.
Source

Questions about rs13360092

What is rs13360092?

rs13360092 is a single position in the genome, in or near the ISL1 gene. Published research associates it with verbal declarative memory. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13360092 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13360092 come from?

GWAS Catalog, Biological psychiatry 2015, PMID:25648963. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Verbal declarative memory (rs13360092). MyGeneLog™. https://www.mygenelog.com/variants/rs13360092

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