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Omega-6 fatty acids to total fatty acids percentage

near HMGCR · rs13354746

What the study found

Who was studied 110,346 European ancestry males.

The effect The reported allele is T; the catalogue records no effect size ; p = 4 × 10−11.

Where it sits Chromosome 5, band 5q13.3 — between genes, 13 kb from HMGCR.

What each result means

C/C No copy of the version the research linked to Omega-6 fatty acids to total fatty acids percentage. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Omega-6 fatty acids to total fatty acids percentage. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Omega-6 fatty acids to total fatty acids percentage. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13354746

What is rs13354746?

rs13354746 is a single position in the genome, in or near the near HMGCR gene. Published research associates it with omega-6 fatty acids to total fatty acids percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13354746 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13354746 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Omega-6 fatty acids to total fatty acids percentage (rs13354746). MyGeneLog™. https://www.mygenelog.com/variants/rs13354746

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