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IgA nephropathy

ITGAX · rs13332545

Where this position leads

Condition: IgA Nephropathy

rs13332545 Condition: IgA Nephropathy IgA Nephropathy Condition rs13332545 rs13332545 ITGAX

What the study found

Who was studied 3,616 Han Chinese ancestry cases, 10,417 Han Chinese ancestry controls.

The effect Each copy of the C allele carried 0.80 times the odds of IgA nephropathy (95% confidence interval 0.75-0.86); p = 1 × 10−8.

How common The C allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 16, band 16p11.2 — in an intron of ITGAX.

What each result means

C/C Two copies of the version the research linked to IgA nephropathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to IgA nephropathy. That is a smaller link than two copies.
T/T No copy of the version the research linked to IgA nephropathy. This is the starting point the study compared everyone against.
Source

Questions about rs13332545

What is rs13332545?

rs13332545 is a single position in the genome, in or near the ITGAX gene. Published research associates it with iga nephropathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13332545 linked to?

On MyGeneLog this position is linked to IgA Nephropathy. The research behind each link, and its sources, are set out on that condition page.

Does having rs13332545 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13332545 come from?

GWAS Catalog, Frontiers of medicine 2024, PMID:39343836. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

IgA nephropathy (rs13332545). MyGeneLog™. https://www.mygenelog.com/variants/rs13332545

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