0 463237122224Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity3Meta AI7Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 3,442 European ancestry adenocarcinoma cases, 3,275 European ancestry squamous cell carcinoma cases, 4,631 cases, up to 15,861 controls; replicated in 3,589 European ancestry adenocarcinoma cases, 3,202 European ancestry squamous cell carcinoma cases, 3,455 cases, up to 38,295 controls.
The effect
Each copy of the T allele carried 1.13 times the odds of Lung cancer (95% confidence interval 1.09-1.18); p = 7 × 10−10.
How common The T allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 3, band 3q28 — in an intron of TP63.
What ClinVar records
ClassificationBenign for TP63-Related Spectrum Disorders; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2025-02-03.
ClinVar record 1167533NM_003722.5(TP63):c.62+8236T>C
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Lung cancer. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Lung cancer. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2014 · PMID 24880342 · open access
Questions about rs13314271
What is rs13314271?
rs13314271 is a single position in the genome, in or near the TP63 gene. Published research associates it with lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs13314271 linked to?
On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs13314271 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13314271 come from?
GWAS Catalog, Nat Genet 2014, PMID:24880342. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 463237122224Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity3Meta AI7Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others24Total46Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Lung cancer (rs13314271). MyGeneLog™. https://www.mygenelog.com/variants/rs13314271