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Hemoglobin

near PES1P2 · rs13302409

Where this position leads

Conditions: Colon Polyp, Blood Cell Counts

rs13302409 Condition: Colon Polyp Colon Polyp Condition Condition: Blood Cell Counts Blood Cell Counts Condition rs13302409 rs13302409 near PES1P2

What the study found

Who was studied 350,474 European ancestry individuals, 152,447 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0221 lower (95% confidence interval 0.018-0.026); p = 1 × 10−30.

Where it sits Chromosome 9, band 9p23 — between genes, 10.2 kb from PES1P2.

What each result means

C/C Two copies of the version the research linked to Hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Hemoglobin. That is a smaller link than two copies.
T/T No copy of the version the research linked to Hemoglobin. This is the starting point the study compared everyone against.
Source
A cross-population atlas of genetic associations for 220 human phenotypes
Sakaue S, Kanai M, Tanigawa Y, Karjalainen J, Kurki M, Koshiba S, Narita A, Konuma T, Yamamoto K, Akiyama M, Ishigaki K, Suzuki A
and 34 more — show all
Suzuki K, Obara W, Yamaji K, Takahashi K, Asai S, Takahashi Y, Suzuki T, Shinozaki N, Yamaguchi H, Minami S, Murayama S, Yoshimori K, Nagayama S, Obata D, Higashiyama M, Masumoto A, Koretsune Y, Ito K, Terao C, Yamauchi T, Komuro I, Kadowaki T, Tamiya G, Yamamoto M, Nakamura Y, Kubo M, Murakami Y, Yamamoto K, Kamatani Y, Palotie A, Rivas MA, Daly MJ, Matsuda K, Okada Y
FinnGen
Nature genetics · 2021 · PMID 34594039

Questions about rs13302409

What is rs13302409?

rs13302409 is a single position in the genome, in or near the near PES1P2 gene. Published research associates it with hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13302409 linked to?

On MyGeneLog this position is linked to Colon Polyp, Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs13302409 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13302409 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hemoglobin (rs13302409). MyGeneLog™. https://www.mygenelog.com/variants/rs13302409

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