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Eye color

LURAP1L-AS1 · rs13297008

Where this position leads

Condition: Eye Color and Pigmentation

rs13297008 Condition: Eye Color and Pigmentation Eye Color and Pigmentation Condition rs13297008 rs13297008 LURAP1L-AS1

What the study found

Who was studied 157,485 European ancestry individuals; replicated in 35,501 European ancestry individuals, 959 Han Chinese ancestry individuals, 677 Indian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.26 higher (95% confidence interval 0.24-0.28); p = 5 × 10−250.

How common The G allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 9, band 9p23 — in an intron of LURAP1L-AS1.

What each result means

A/A No copy of the version the research linked to Eye color. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Eye color. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Eye color. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13297008

What is rs13297008?

rs13297008 is a single position in the genome, in or near the LURAP1L-AS1 gene. Published research associates it with eye color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13297008 linked to?

On MyGeneLog this position is linked to Eye Color and Pigmentation. The research behind each link, and its sources, are set out on that condition page.

Does having rs13297008 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13297008 come from?

GWAS Catalog, Science advances 2021, PMID:33692100. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eye color (rs13297008). MyGeneLog™. https://www.mygenelog.com/variants/rs13297008

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