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Ankle injury

NFIB · rs13286037

What the study found

Who was studied 1,421 European ancestry cases, 154 Hispanic/Latino cases, 121 East Asian ancestry cases, 81,843 European ancestry controls, 8,406 Hispanic/Latino controls, 7,397 East Asian ancestry controls.

The effect Each copy of the A allele carried 1.63 times the odds of Ankle injury (95% confidence interval 1.46-1.8); p = 5 × 10−8.

How common The A allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 9, band 9p22.3 — in an intron of NFIB.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Ankle injury compared to the general population.
A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Ankle injury.
T/T Published research associates this genotype with typical/baseline likelihood of Ankle injury — no copies of the reported risk allele.
Source

Questions about rs13286037

What is rs13286037?

rs13286037 is a single position in the genome, in or near the NFIB gene. Published research associates it with ankle injury. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13286037 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13286037 come from?

GWAS Catalog, PLoS One 2017, PMID:28957384. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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