Sensitive

Prostate cancer

near NKX3-1 · rs13274763

Where this position leads

Condition: Prostate Cancer

rs13274763 Condition: Prostate Cancer Prostate Cancer Condition rs13274763 rs13274763 near NKX3-1

What the study found

Who was studied 1,844 Taiwanese ancestry cases, 80,709 Taiwanese ancestry controls.

The effect Each copy of the G allele carried 1.38 times the odds of Prostate cancer (95% confidence interval 1.29-1.48); p = 5 × 10−19.

How common The G allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 8, band 8p21.2 — between genes, 17.4 kb from NKX3-1.

What each result means

A/A No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13274763

What is rs13274763?

rs13274763 is a single position in the genome, in or near the near NKX3-1 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13274763 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs13274763 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13274763 come from?

GWAS Catalog, Molecular carcinogenesis 2024, PMID:38390760. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs13274763). MyGeneLog™. https://www.mygenelog.com/variants/rs13274763

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