Sensitive

Schizophrenia

CSMD1 · rs13261217

Where this position leads

Condition: Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk)

rs13261217 Condition: Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk) Autism Spectrum Disorder and Schizo… Condition rs13261217 rs13261217 CSMD1

What the study found

Who was studied 7,699 Chinese ancestry cases, 35,476 European ancestry cases, 18,327 Chinese ancestry controls, 46,839 European ancestry controls; replicated in 4,384 Chinese ancestry cases, 5,770 Chinese ancestry controls.

The effect Each copy of the G allele carried 1.07 times the odds of Schizophrenia (95% confidence interval 1.05-1.09); p = 2 × 10−9.

Where it sits Chromosome 8, band 8p23.2 — in a non-coding transcript of CSMD1.

What each result means

A/A No copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13261217

What is rs13261217?

rs13261217 is a single position in the genome, in or near the CSMD1 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13261217 linked to?

On MyGeneLog this position is linked to Autism Spectrum Disorder and Schizophrenia (Shared Genetic Risk). The research behind each link, and its sources, are set out on that condition page.

Does having rs13261217 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13261217 come from?

GWAS Catalog, Nature genetics 2017, PMID:28991256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs13261217). MyGeneLog™. https://www.mygenelog.com/variants/rs13261217

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