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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 98,060 European ancestry active cases, 162,995 European ancestry inactive controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 9 × 10−11.
How common The G allele had a frequency of about 61% in the people studied.
Where it sits Chromosome 7, band 7q33 — in an intron of EXOC4.
What each result means
A/ANo copy of the version the research linked to Vigorous physical activity. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Vigorous physical activity. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Vigorous physical activity. That is the strongest link of the three results. A link in a study is not a diagnosis.
International journal of obesity (2005) · 2018 · PMID 29899525 · open access
Questions about rs13243553
What is rs13243553?
rs13243553 is a single position in the genome, in or near the EXOC4 gene. Published research associates it with vigorous physical activity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs13243553 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13243553 come from?
GWAS Catalog, Int J Obes (Lond) 2018, PMID:29899525. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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