Sensitive

Systemic lupus erythematosus

TPI1P2 · rs13239597

Where this position leads

Condition: Systemic Lupus Erythematosus

rs13239597 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs13239597 rs13239597 TPI1P2

What the study found

Who was studied 427 European ancestry cases, 89,699 European ancestry controls.

The effect Each copy of the A allele carried 1.91 times the odds of Systemic lupus erythematosus (95% confidence interval 1.2-3.03); p = 4 × 10−14.

How common The A allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 7, band 7q32.1 — in a non-coding transcript of TPI1P2.

What each result means

A/A Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
C/C No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
Source

Questions about rs13239597

What is rs13239597?

rs13239597 is a single position in the genome, in or near the TPI1P2 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13239597 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does having rs13239597 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13239597 come from?

GWAS Catalog, Joint bone spine 2022, PMID:35167971. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systemic lupus erythematosus (rs13239597). MyGeneLog™. https://www.mygenelog.com/variants/rs13239597

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