Sensitive

Carpal tunnel syndrome

near CRPPA · rs13221870

Where this position leads

Condition: Carpal Tunnel Syndrome

rs13221870 Condition: Carpal Tunnel Syndrome Carpal Tunnel Syndrome Condition rs13221870 rs13221870 near CRPPA

What the study found

Who was studied 18,855 European ancestry cases, 461,346 European ancestry controls, 192 East Asian ancestry cases, 178,534 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0695 higher (95% confidence interval 0.048-0.091); p = 2 × 10−10.

Where it sits Chromosome 7, band 7p21.2 — between genes, 15 kb from CRPPA.

What each result means

A/A Two copies of the version the research linked to Carpal tunnel syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Carpal tunnel syndrome. That is a smaller link than two copies.
G/G No copy of the version the research linked to Carpal tunnel syndrome. This is the starting point the study compared everyone against.
Source

Questions about rs13221870

What is rs13221870?

rs13221870 is a single position in the genome, in or near the near CRPPA gene. Published research associates it with carpal tunnel syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13221870 linked to?

On MyGeneLog this position is linked to Carpal Tunnel Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs13221870 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13221870 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Carpal tunnel syndrome (rs13221870). MyGeneLog™. https://www.mygenelog.com/variants/rs13221870

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