Sensitive

Lewy body dementia (MTAG)

TREML2 · rs13216201

What the study found

Who was studied 2,591 European ancestry cases, 4,027 European ancestry controls.

The effect Each copy of the T allele shifted the measure 6.12 Z score lower; p = 9 × 10−10.

How common The T allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 6, band 6p21.1 — in an intron of TREML2.

What each result means

G/G No copy of the version the research linked to Lewy body dementia (MTAG). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Lewy body dementia (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Lewy body dementia (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13216201

What is rs13216201?

rs13216201 is a single position in the genome, in or near the TREML2 gene. Published research associates it with lewy body dementia (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13216201 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13216201 come from?

GWAS Catalog, BMC medicine 2022, PMID:35729600. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lewy body dementia (MTAG) (rs13216201). MyGeneLog™. https://www.mygenelog.com/variants/rs13216201

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