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Inguinal hernia

H2BC4 · rs13212652

Where this position leads

Condition: Inguinal Hernia

rs13212652 Condition: Inguinal Hernia Inguinal Hernia Condition rs13212652 rs13212652 H2BC4

What the study found

Who was studied 18,791 European ancestry cases, 93,955 European ancestry controls.

The effect Each copy of the T allele carried 1.12 times the odds of Inguinal hernia (95% confidence interval 1.08-1.15); p = 3 × 10−11.

How common The T allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 6, band 6p22.2 — inside H2BC4.

What each result means

G/G No copy of the version the research linked to Inguinal hernia. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Inguinal hernia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Inguinal hernia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13212652

What is rs13212652?

rs13212652 is a single position in the genome, in or near the H2BC4 gene. Published research associates it with inguinal hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13212652 linked to?

On MyGeneLog this position is linked to Inguinal Hernia. The research behind each link, and its sources, are set out on that condition page.

Does having rs13212652 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13212652 come from?

GWAS Catalog, PloS one 2022, PMID:36584111. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Inguinal hernia (rs13212652). MyGeneLog™. https://www.mygenelog.com/variants/rs13212652

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