0 14626Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot6Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others6Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
1 / 4
Its strongest genetic-study result is p = 10−11, with 2 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 321,047 European ancestry individuals; replicated in 24,218 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0212 higher (95% confidence interval 0.015-0.027); p = 1 × 10−11.
How common The A allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 6, band 6q13 — in an intron of KCNQ5.
What each result means
A/ATwo copies of the version the research linked to Peak expiratory flow. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Peak expiratory flow. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Peak expiratory flow. This is the starting point the study compared everyone against.
Nature genetics · 2019 · PMID 30804560 · open access
Questions about rs13206405
What is rs13206405?
rs13206405 is a single position in the genome, in or near the KCNQ5 gene. Published research associates it with peak expiratory flow. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs13206405 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13206405 come from?
GWAS Catalog, Nature genetics 2019, PMID:30804560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 14626Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot6Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others6Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.