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Osteoporosis

ALDH7A1 · rs13182402

Where this position leads

Condition: Osteoporosis

rs13182402 Condition: Osteoporosis Osteoporosis Condition rs13182402 rs13182402 ALDH7A1

What the study found

Who was studied 350 Han Chinese ancestry cases, 350 Han Chinese ancestry controls; replicated in 390 Han Chinese ancestry cases, 516 Han Chinese ancestry controls.

The effect Each copy of the G allele carried 2.25 times the odds of Osteoporosis (95% confidence interval 1.72-2.94); p = 2 × 10−9.

How common The G allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 5, band 5q23.2 — in an intron of ALDH7A1.

What each result means

A/A No copy of the version the research linked to Osteoporosis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Osteoporosis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Osteoporosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs13182402

What is rs13182402?

rs13182402 is a single position in the genome, in or near the ALDH7A1 gene. Published research associates it with osteoporosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13182402 linked to?

On MyGeneLog this position is linked to Osteoporosis. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs13182402?

Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs13182402 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13182402 come from?

GWAS Catalog, PLoS Genet 2010, PMID:20072603. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Osteoporosis (rs13182402). MyGeneLog™. https://www.mygenelog.com/variants/rs13182402

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