Sensitive

Lung cancer

TERT · rs13167280

Where this position leads

What the study found

Who was studied 22,299 East Asian ancestry cases, 225,690 East Asian ancestry controls, 31,351 European ancestry cases, 260,520 European ancestry controls.

The effect Each copy of the A allele carried 1.20 times the odds of Lung cancer (95% confidence interval 1.17-1.23); p = 4 × 10⁻³⁷.

How common The A allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 5, band 5p15.33 — in an intron of TERT.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-09-14. ClinVar record 1274097 NM_198253.3(TERT):c.1770-24C>T

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A Two copies of the version the research linked to Lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.

A/G One copy of the version the research linked to Lung cancer. That is a smaller link than two copies.

G/G No copy of the version the research linked to Lung cancer. This is the starting point the study compared everyone against.

Source

Genome-wide meta-analysis across East Asian and European populations provides insights into the molecular basis of lung cancer

Zhu M, Zhang C, Han Y, Jin C, Miao S, Zhang J, Gong L, Mou Y, Ji C, Fu Y, Zhang E, Yu C

and 17 more — show all

Sun D, Jiang Y, Chen J, Yang L, Chen Y, Du H, Walters R, Millwood I, Dai J, Chen Z, Hu Z, Lv J, Jin G, Amos CI, Shen H, Li L, Ma H

Genome medicine · 2026 · PMID 42152146 · open access

Questions about rs13167280

What is rs13167280?

rs13167280 is a single position in the genome, in or near the TERT gene. Published research associates it with lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13167280 linked to?

On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs13167280 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13167280 come from?

GWAS Catalog, Genome medicine 2026, PMID:42152146. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung cancer (rs13167280). MyGeneLog™. https://www.mygenelog.com/variants/rs13167280

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