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Medial thalamic nuclei volume

GMNC · rs1316356

What the study found

Who was studied 30,114 white British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0656 higher (95% confidence interval 0.049-0.082); p = 8 × 10−15.

How common The C allele had a frequency of about 38% in the people studied.

Where it sits Chromosome 3, band 3q28 — between genes, 46.9 kb from GMNC.

What each result means

C/C Two copies of the version the research linked to Medial thalamic nuclei volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Medial thalamic nuclei volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Medial thalamic nuclei volume. This is the starting point the study compared everyone against.
Source

Questions about rs1316356

What is rs1316356?

rs1316356 is a single position in the genome, in or near the GMNC gene. Published research associates it with medial thalamic nuclei volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1316356 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1316356 come from?

GWAS Catalog, Nature communications 2021, PMID:34006833. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Medial thalamic nuclei volume (rs1316356). MyGeneLog™. https://www.mygenelog.com/variants/rs1316356

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