Standard
Estimated glomerular filtration rate
RAI14 · rs13157326
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 567,460 European ancestry individuals, 165,726 East Asian ancestry individuals, 13,842 African American individuals, 13,359 South Asian ancestry individuals, 4,961 Hispanic individuals; replicated in 216,518 European ancestry individuals, 64,204 non-Hispanic black individuals.
The effect
Each copy of the A allele shifted the measure 0.0027 lower (95% confidence interval 0.0021-0.0033); p = 1 × 10−25.
How common The A allele had a frequency of about 45% in the people studied.
Where it sits Chromosome 5, band 5p13.2 — between genes, 147.3 kb from RAI14-DT.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Estimated glomerular filtration rate compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Estimated glomerular filtration rate.
G/G
Published research associates this genotype with typical/baseline likelihood of Estimated glomerular filtration rate — no copies of the reported risk allele.
Source
A catalog of genetic loci associated with kidney function from analyses of a million individuals
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Nature genetics · 2019 · PMID 31152163
Questions about rs13157326
What is rs13157326?
rs13157326 is a single position in the genome, in or near the RAI14 gene. Published research associates it with estimated glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs13157326 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13157326 come from?
GWAS Catalog, Nature genetics 2019, PMID:31152163. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Estimated glomerular filtration rate (rs13157326). MyGeneLog™. https://www.mygenelog.com/variants/rs13157326
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