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Lifetime smoking index

TENM2 · rs13153393

What the study found

Who was studied 462,690 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.02 lower (95% confidence interval 0.014-0.026); p = 3 × 10−10.

How common The A allele had a frequency of about 88% in the people studied.

Where it sits Chromosome 5, band 5q34 — in an intron of TENM2.

What each result means

A/A Two copies of the version the research linked to Lifetime smoking index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lifetime smoking index. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lifetime smoking index. This is the starting point the study compared everyone against.
Source

Questions about rs13153393

What is rs13153393?

rs13153393 is a single position in the genome, in or near the TENM2 gene. Published research associates it with lifetime smoking index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13153393 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13153393 come from?

GWAS Catalog, Psychological medicine 2020, PMID:31689377. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lifetime smoking index (rs13153393). MyGeneLog™. https://www.mygenelog.com/variants/rs13153393

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