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Age-related hearing impairment

CLRN2 · rs13148153

What the study found

Who was studied 147,997 European ancestry cases, 575,269 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0098 higher (95% confidence interval 0.0071-0.0125); p = 3 × 10−12.

How common The T allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 4, band 4p15.32 — in an intron of CLRN2.

What each result means

C/C No copy of the version the research linked to Age-related hearing impairment. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Age-related hearing impairment. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Age-related hearing impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs13148153

What is rs13148153?

rs13148153 is a single position in the genome, in or near the CLRN2 gene. Published research associates it with age-related hearing impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13148153 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13148153 come from?

GWAS Catalog, American journal of human genetics 2022, PMID:35580588. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age-related hearing impairment (rs13148153). MyGeneLog™. https://www.mygenelog.com/variants/rs13148153

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