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Who was studied 296,989 European ancestry individuals, 80,764 African American individuals, 31,877 Hispanic American individuals.
The effect
Each copy of the A allele shifted the measure 8.21 z score higher; p = 2 × 10−16.
How common The A allele had a frequency of about 61% in the people studied.
Where it sits Chromosome 4, band 4p14 — in an intron of KLB.
What each result means
A/ATwo copies of the version the research linked to Alcohol use disorder (consumption score). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Alcohol use disorder (consumption score). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Alcohol use disorder (consumption score). This is the starting point the study compared everyone against.
The American journal of psychiatry · 2023 · PMID 37282553
Questions about rs13146907
What is rs13146907?
rs13146907 is a single position in the genome, in or near the KLB gene. Published research associates it with alcohol use disorder (consumption score). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs13146907 linked to?
On MyGeneLog this position is linked to Alcohol Use Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs13146907 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13146907 come from?
GWAS Catalog, The American journal of psychiatry 2023, PMID:37282553. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1512219Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alcohol use disorder (consumption score) (rs13146907). MyGeneLog™. https://www.mygenelog.com/variants/rs13146907