Standard

Diastolic blood pressure

NFKB1-AS1 · rs13140033

Where this position leads

Condition: Blood Pressure

rs13140033 Condition: Blood Pressure Blood Pressure Condition rs13140033 rs13140033 NFKB1-AS1

What the study found

Who was studied 322,141 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 9.26 z score lower; p = 2 × 10−20.

Where it sits Chromosome 4, band 4q24 — in an intron of NFKB1-AS1.

What each result means

A/A Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs13140033

What is rs13140033?

rs13140033 is a single position in the genome, in or near the NFKB1-AS1 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13140033 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs13140033 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13140033 come from?

GWAS Catalog, HGG advances 2025, PMID:39663699. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs13140033). MyGeneLog™. https://www.mygenelog.com/variants/rs13140033

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