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Who was studied 296,989 European ancestry individuals.
The effect
Each copy of the A allele carried 0.96 times the odds of Alcohol use disorder (95% confidence interval 0.94-0.97); p = 9 × 10−11.
How common The A allele had a frequency of about 46% in the people studied.
Where it sits Chromosome 4, band 4p14 — between genes, 3.3 kb from KLB.
What each result means
A/ATwo copies of the version the research linked to Alcohol use disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Alcohol use disorder. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Alcohol use disorder. This is the starting point the study compared everyone against.
The American journal of psychiatry · 2023 · PMID 37282553
Questions about rs13130101
What is rs13130101?
rs13130101 is a single position in the genome, in or near the near KLB gene. Published research associates it with alcohol use disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs13130101 linked to?
On MyGeneLog this position is linked to Alcohol Use Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs13130101 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13130101 come from?
GWAS Catalog, The American journal of psychiatry 2023, PMID:37282553. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alcohol use disorder (rs13130101). MyGeneLog™. https://www.mygenelog.com/variants/rs13130101