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Who was studied 711 African American or Afro-Caribbean cases, 120,893 African American or Afro-Caribbean controls, 8,704 European ancestry cases, 440,252 European ancestry controls, 678 Hispanic or Latin American cases, 59,052 Hispanic or Latin American controls.
The effect
Each copy of the A allele shifted the measure 3.35 lower (95% confidence interval 3.33-3.37); p = 4 × 10−11.
How common The A allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 1, band 1p33 — in an intron of SPATA6.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Parkinson's disease compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Parkinson's disease.
G/GPublished research associates this genotype with typical/baseline likelihood of Parkinson's disease — no copies of the reported risk allele.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs1311506805
What is rs1311506805?
rs1311506805 is a single position in the genome, in or near the SPATA6 gene. Published research associates it with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1311506805 linked to?
On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs1311506805 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1311506805 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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