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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 51,800 European ancestry cases, 1,087,070 European ancestry controls.
The effect
Each copy of the G allele carried 1.04 times the odds of Dyslexia (95% confidence interval 1.029-1.058); p = 1 × 10−9.
How common The G allele had a frequency of about 58% in the people studied.
Where it sits Chromosome 3, band 3p13 — in an intron of MITF.
What each result means
C/CNo copy of the version the research linked to Dyslexia. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Dyslexia. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Dyslexia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2022 · PMID 36266505 · open access
Questions about rs13097431
What is rs13097431?
rs13097431 is a single position in the genome, in or near the MITF gene. Published research associates it with dyslexia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs13097431 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13097431 come from?
GWAS Catalog, Nature genetics 2022, PMID:36266505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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