FYCO1 · rs13079478
Where this position leads
Condition: Osteoarthritis
What the study found
Who was studied 314,870 European ancestry individuals with osteoarthritis data, 1,887,658 European ancestry individuals with COVID-19 hospitalization data.
The effect Each copy of the T allele shifted the measure 0.028 higher (95% confidence interval 0.022-0.034); p = 1 × 10−25.
Where it sits Chromosome 3, band 3p21.31 — a missense change in FYCO1.
What ClinVar records
Classification
Benign for Cataract 18; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 6 submitters), last evaluated 2026-01-27.
ClinVar record 261729 NM_024513.4(FYCO1):c.3003C>A (p.Asn1001Lys)
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs13079478 is a single position in the genome, in or near the FYCO1 gene. Published research associates it with covid-19 hospitalization or osteoarthritis (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Frontiers in immunology 2023, PMID:37398645. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
COVID-19 hospitalization or osteoarthritis (MTAG) (rs13079478). MyGeneLog™. https://www.mygenelog.com/variants/rs13079478