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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 34,930 East Asian ancestry individuals, 187,167 European ancestry individuals; replicated in 8,741 Chinese ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−9.
How common The A allele had a frequency of about 85% in the people studied.
Where it sits Chromosome 3, band 3q22.1 — in an intron of CPNE4.
What each result means
A/ATwo copies of the version the research linked to HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to HDL cholesterol levels. That is a smaller link than two copies.
C/CNo copy of the version the research linked to HDL cholesterol levels. This is the starting point the study compared everyone against.
rs13076253 is a single position in the genome, in or near the ACAD11 gene. Published research associates it with hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs13076253 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13076253 come from?
GWAS Catalog, Human molecular genetics 2017, PMID:28334899. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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