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Psoriasis

REL-DT · rs1306395

Where this position leads

Condition: Psoriasis

rs1306395 Condition: Psoriasis Psoriasis Condition rs1306395 rs1306395 REL-DT

What the study found

Who was studied 20,105 European ancestry cases, 842,975 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.111 higher (95% confidence interval 0.081-0.14); p = 1 × 10−13.

How common The T allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 2, band 2p16.1 — in an intron of REL-DT.

What each result means

C/C No copy of the version the research linked to Psoriasis. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Psoriasis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Psoriasis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1306395

What is rs1306395?

rs1306395 is a single position in the genome, in or near the REL-DT gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1306395 linked to?

On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs1306395 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1306395 come from?

GWAS Catalog, Briefings in bioinformatics 2024, PMID:39883516. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Psoriasis (rs1306395). MyGeneLog™. https://www.mygenelog.com/variants/rs1306395

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