0 13143212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot3Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others2Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 42,490 European ancestry cases, 773,420 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0576 log odds ratio lower (95% confidence interval 0.04-0.076); p = 3 × 10−10.
Where it sits Chromosome 21, band 21q21.1 — between genes, 80 kb from CYCSP42.
What each result means
C/CNo copy of the version the research linked to Hashimoto thyroiditis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Hashimoto thyroiditis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Hashimoto thyroiditis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2026 · PMID 42527560 · open access
Questions about rs13052469
What is rs13052469?
rs13052469 is a single position in the genome, in or near the near CYCSP42 gene. Published research associates it with hashimoto thyroiditis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs13052469 linked to?
On MyGeneLog this position is linked to Lymphocytic Thyroiditis (Hashimoto's). The research behind each link, and its sources, are set out on that condition page.
Does having rs13052469 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13052469 come from?
GWAS Catalog, Nature genetics 2026, PMID:42527560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 13143212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot3Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others2Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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