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Estimated glomerular filtration rate in non-diabetics

NCOA6 · rs13040449

What the study found

Who was studied 152,624 European ancestry individuals, 36,369 African American individuals.

The effect Each copy of the A allele shifted the measure 0.575 lower (95% confidence interval 0.47-0.68); p = 2 × 10−24.

How common The A allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 20, band 20q11.22 — in an intron of NCOA6.

What each result means

A/A Two copies of the version the research linked to Estimated glomerular filtration rate in non-diabetics. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Estimated glomerular filtration rate in non-diabetics. That is a smaller link than two copies.
T/T No copy of the version the research linked to Estimated glomerular filtration rate in non-diabetics. This is the starting point the study compared everyone against.
Source

Questions about rs13040449

What is rs13040449?

rs13040449 is a single position in the genome, in or near the NCOA6 gene. Published research associates it with estimated glomerular filtration rate in non-diabetics. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs13040449 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13040449 come from?

GWAS Catalog, Nature communications 2019, PMID:31451708. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate in non-diabetics (rs13040449). MyGeneLog™. https://www.mygenelog.com/variants/rs13040449

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