Standard

Serum protein levels (sST2)

IL1R1 · rs13019803

Where this position leads

What the study found

Who was studied 2,797 individuals.

The effect Each copy of the T allele shifted the measure 0.14 lower (95% confidence interval 0.1-0.18); p = 6 × 10⁻²⁰.

How common The T allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 2, band 2q12.1 — in an intron of IL1R1.

What ClinVar records

Classification association for Ascending aortic dissection; no assertion criteria provided (0 of 4 stars, 1 submitter), last evaluated 2021-02-01. ClinVar record 1120036 NM_000877.4(IL1R1):c.61+1957C>T

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C No copy of the version the research linked to Serum protein levels (sST2). This is the starting point the study compared everyone against.

C/T One copy of the version the research linked to Serum protein levels (sST2). That is a smaller link than two copies.

T/T Two copies of the version the research linked to Serum protein levels (sST2). That is the strongest link of the three results. A link in a study is not a diagnosis.

Source

Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling

Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N

and 12 more — show all

O'Donnell CJ, Dehghan A, Lu C, Levy D, Newton-Cheh C, Lin H, Felix JF, Schreiter ER, Vasan RS, Januzzi JL, Lee RT, Wang TJ

CARDIoGRAM Consortium · CHARGE Inflammation Working Group · CHARGE Heart Failure Working Group

The Journal of clinical investigation · 2013 · PMID 23999434

What people read about alongside this

Heart and circulation1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs13019803

What is rs13019803?

rs13019803 is a single position in the genome, in or near the IL1R1 gene. Published research associates it with serum protein levels (sst2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13019803 linked to?

On MyGeneLog this position is linked to Serum sST2 Levels. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs13019803?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs13019803 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13019803 come from?

GWAS Catalog, J Clin Invest 2013, PMID:23999434. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum protein levels (sST2) (rs13019803). MyGeneLog™. https://www.mygenelog.com/variants/rs13019803

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