Sensitive

Type 1 diabetes

SEPT2 · rs13018977

Where this position leads

Condition: Type 1 Diabetes

rs13018977 Condition: Type 1 Diabetes Type 1 Diabetes Condition rs13018977 rs13018977 SEPT2

What the study found

Who was studied 18,942 European ancestry cases, 501,638 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.1 higher (95% confidence interval 0.065-0.135); p = 2 × 10−8.

How common The A allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 2, band 2q37.3 — in an intron of SEPTIN2.

What each result means

A/A Two copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
Source

Questions about rs13018977

What is rs13018977?

rs13018977 is a single position in the genome, in or near the SEPT2 gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs13018977 linked to?

On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs13018977 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs13018977 come from?

GWAS Catalog, Nature 2021, PMID:34012112. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 1 diabetes (rs13018977). MyGeneLog™. https://www.mygenelog.com/variants/rs13018977

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