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Who was studied 2,418 European ancestry cases, 4,504 European ancestry controls; replicated in 2,604 cases, 2,882 controls.
The effect
Each copy of the A allele carried 1.21 times the odds of Rheumatoid arthritis (95% confidence interval 1.15-1.28); p = 2 × 10−12.
How common The A allele had a frequency of about 34% in the people studied.
Where it sits Chromosome 2, band 2p16.1 — in a non-coding transcript of NONOP2.
What each result means
A/ATwo copies of the version the research linked to Rheumatoid arthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Rheumatoid arthritis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Rheumatoid arthritis. This is the starting point the study compared everyone against.
Nature genetics · 2009 · PMID 19503088 · open access
Questions about rs13017599
What is rs13017599?
rs13017599 is a single position in the genome, in or near the REL gene. Published research associates it with rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs13017599 linked to?
On MyGeneLog this position is linked to Rheumatoid Arthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs13017599 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs13017599 come from?
GWAS Catalog, Nat Genet 2009, PMID:19503088. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 403225113221Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI5Microsoft · Copilot1Amazon1Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others21Total40Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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